Nootropics: An Introduction

Nootropics, also known as smart drugs, are a class of cognitive-enhancing supplements that have gained popularity in recent years. They are ...

06 May

How Nootropics Boost Mental Clarity and Focus

The mechanisms through which nootropics improve mental clarity and focus can vary depending on the specific substance, but many of them act on the brain's neurotransmitter systems, blood flow, and energy metabolism.

Some of the key ways that nootropics may boost mental clarity and focus include:

1. Increasing neurotransmitter activity: Many nootropics, such as racetams and choline, are thought to work by increasing the activity of neurotransmitters like acetylcholine, which play a key role in learning and memory.

2. Improving blood flow: Some nootropics, such as vinpocetine and ginkgo biloba, are believed to work by improving blood flow to the brain. This increased blood flow can improve oxygen and nutrient delivery to brain cells, which may enhance cognitive function.

3. Boosting energy metabolism: Nootropics such as creatine and rhodiola rosea are believed to work by improving energy metabolism in the brain, helping to improve focus and mental clarity.

4. Reducing stress and anxiety: Some nootropics, such as ashwagandha and L-theanine, may help to reduce stress and anxiety, which can improve mental clarity and focus.

There have been numerous studies investigating the effects of various nootropics on cognitive function. For example, a meta-analysis published in Drugs found that piracetam, a popular nootropic, was associated with significant improvements in cognitive function in elderly individuals with cognitive impairment (Malykh and Sadaie, 2010).

Another study published in Appetite found that a combination of a multi-vitamin with added guarana  improved cognitive function and mood in healthy young adults (Kennedy, et al., 2007).

While the research on nootropics is still in its early stages and more studies are needed to fully understand their effects, these findings suggest that nootropics may be useful for improving mental clarity and focus in certain individuals.


Kennedy, D.O., et al. (2007). Improved cognitive performance and mental fatigue following a multi-vitamin and mineral supplement with added guaranĂ¡ (Paullinia cupana). Appetite. 2008 Mar-May;50(2-3):506-13. doi: 10.1016/j.appet.2007.10.007. Epub 2007 Oct 30. PMID: 18077056.

Malykh, A.G. and Sadaie, M.R. (2010). Piracetam and piracetam-like drugs: from basic science to novel clinical applications to CNS disorders. Drugs, 70(3), 287-312.